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Balancing Act: The Case for Dog Hormone Replacement Therapy After Spaying or Neutering

Although not favored in many other countries, spaying and neutering are common practices in the United States for controlling canine overpopulation.  While procedures help control the pet population, recent science has shown that the procedures may in fact negatively affect the long term health of our canine companions. That is because the removal of sex hormones can lead to a host of physical and emotional changes in our dogs similar to what is found in their human counterparts.
In this blog, we will explore the need for Dog Hormone Replacement Therapy (DHRT) after spaying or neutering.

Understanding the Impact

Spaying and neutering entail the surgical removal of a dog's reproductive organs, resulting in the loss of key sex hormones, such as estrogen and testosterone. While these procedures are useful for reducing overpopulation and preventing certain diseases, they have side effects that can affect a dog's health and behavior.

Physical Health Implications

The removal of sex hormones can have a significant impact on a dog's physical health. For female dogs, spaying can lead to an increased risk of urinary incontinence, obesity, and certain types of cancers. In male dogs, neutering can similarly contribute to weight gain and an increased risk of certain cancers, as well as joint and orthopedic issues.

Behavioral Changes

Sex hormones play a vital role in a dog's behavior and temperament. Removal of these hormones can lead to various behavioral changes. In some cases, dogs may become more prone to anxiety, aggression, and reactivity. They may also exhibit changes in playfulness and sociability.

In female dogs, spaying can sometimes lead to a loss of maternal instincts and, in some cases, increased aggression. In males, neutering may reduce territorial marking behavior but can also lead to a loss of confidence or fear-based aggression.

The Case for DHRT

Dog Hormone Replacement Therapy offers a potential solution to mitigate the side effects of spaying and neutering. By reintroducing a controlled amount of hormones, DHRT can help dogs maintain a healthier balance, both physically and behaviorally.

Here are some reasons why DHRT may be necessary:

1. Health Maintenance: DHRT can help prevent the physical issues associated with hormone loss, such as obesity and orthopedic problems, allowing dogs to live longer and healthier lives.

2. Behavioral Stabilization: DHRT can help stabilize behavioral changes, making it easier for dogs to adjust to their altered hormonal state and reducing the likelihood of aggression, anxiety, or reactivity.

3. Quality of Life: Dogs that undergo DHRT may enjoy an improved quality of life with fewer behavioral issues, resulting in a more harmonious relationship with their human families.

Consult with Your Veterinarian

Before considering DHRT for your spayed or neutered dog, it's crucial to consult with a veterinarian. They can evaluate your dog's specific needs and recommend the best course of action. DHRT should be administered under professional guidance, as hormone levels need to be carefully monitored to ensure optimal health and well-being.

In conclusion, because spaying and neutering of canines is so widespread a practice, it's important for dog owners to be aware of the potential consequences of these procedures. Dog Hormone Replacement Therapy can play a vital role in mitigating these effects and helping dogs lead healthier, more balanced lives. Remember, every dog is unique, so the decision to pursue DHRT should always be made in consultation with a trusted veterinarian who understands your pet's specific needs.

For more information on the effects of spaying and neutering, visit the PABS Science link on our website,

We also invite you to read the article title: Hormone Restoration in Dogs, by the Parsemus Foundation.

Lastly, if you are still deciding whether to spay or neuter your companion, and you want to avoid an accidental litter while you decide, we can help with that.

Please visit to get your dog chastity belt to prevent breeding in the meantime.

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1 comment

No Nonsense / Oct 26, 2023 at 11:07

Are you all completely gone barking mad? 😡
What is wrong with you? Why are you mutilating a healthy dog, and then fill it up with synthetically re-created hormones? Is it not sounding insane to you?
I mean I’m glad that you recognise the latest research that finally shown that spaying and castrating dogs isn’t healthy, as this was always my argument and issue with these barbaric practices – why do humans get HRT, and dogs do not. However humans do not cut out their healthy reproductive organs either…
The heat happens 1 time every 6 months. That’s 2 weeks out of 12 years you need to control your bitch to not overpopulate. And seriously, are America vets still going with the excuse of overpopulation for mutilating the dogs? So freaking barbaric!
SOLUTION – If you’re unable to control your bitch for 2 weeks out of ever 52 weeks, get her tubes tied. The bitch still gets to keep her reproductive organs, and her natural hormones and no puppy responsibilities…
Not all vets do it, because for them it’s just easier for them to mutilate the dogs and cut out the healthy organs. 🤦 🤦‍♀️ 🤦‍♂️

I have 4 dogs, 2 boys and 2 girls. One of the bitches had litter because I planned for it and did artificial insemination. And when I don’t want my girls to have the puppies, I put harness pants on them to block the entry to the… duh… vagina.
And guess what? So far, blocking the entry to vagina worked a treat. 🙄
But it’s madness to say they’re mutilating to avoid the puppies. Do you just let your dogs roam free, are you not supposed to control them ANYWAY?

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